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A key piece of the body s immune response to COVID-19 looks to have been damaged in people who caught the disease before they were vaccinated, a study published this month found, resulting in a major reduction to part of the stanley cup defense the body typically musters to fight off the virus. You have damage that, even in recovery from the infection, you haven t really recovered your ability to make those CD8+ cells. So something happened in the course of infection to prevent that, to damage your response, said Stanford Professor Mark Davis, head of the university s Institute for Immunity, Transplantation and Infection. Davis is lead author of the paper, which was published this month in the journal Immunity.CD4+ T cells, often dubbed helper T cells for their role in marshaling other parts of the immune response, appeared to be undamaged. But Davis and his team found the response of CD8+ T cells, known as killer T cells for their role in destroying infected cells, was substantially worse in people who had survived an infection, with both the quantity and quality of the cells diminished. A disparity remained even after those people got vaccinated with the Pfizer-BioNTech vaccine. Looking at the broader swath of data, we came up with a seven-fold average reduction. B stanley cup ut it was much larger in several of the cases. So that s a big deal, Davis said. While researcher stanley cup s often look to antibodies first to measure the body s initial protection Cnpc Southwest plane that landed at wrong airport gets back in the air
NEW YORK mdash; Authorities are defend af1 ing their response to the suspected abduction of a 2-year-old New York boy who was found dead with his father in Virginia in an apparent murder-suicide. Suffolk County and New York State Police issued a joint statement Thursday amid criticism from Jovani Ligurgo s family for declining to issue an Amber Alert.The agencies say they worked quickly and diligently to locate Jovani and were extremely saddened by his death.Jovani and his 43-year-old father, adidas campus John Ligurgo, were found Wednesday in a Jeep that had been set on fire behind a Raphine home. Each had a gunshot wound. Suffolk police say they provided information to New York State Police for a possible Amber Alert, but state police said the case didn t meet the criteria for one.The agencies say every aspect of the investigation will be thoroughly reviewed. CBS New York reports that Jovani s mother, Maria Busone, had dropped off the boy at Ligurgo s condominium about 7 a.m. Tuesday to spend the day with his father. She alerted police Tuesday after the 43-year-old Ligurgo failed to drop the boy off at her home between 3:30 and 4 p.m., as per a family court visitation order, Suffolk police said. Family told the station that the couple had been involved in a custody dispute.Around the time Busone contacted police, a fire was reported at Ligurgo s home in Coram. Police responded and determined the case to be an arson and that s adidas campus omeone had torche